There are two ways to make an extract of Wild Lettuce. The quick way and the long way. In both cases you will have to dry the wild lettuce first.
The quick way
Boil the herb for 4-5 minutes and let it steep in hot water for an additional 15-20 minutes.
Remove the herb and let the liquid dry out until all that remains is wild lettuce extract.
The long way
You can also soak the herbs in cold water for a total of 10-12 hours.
Remove the herb and let the liquid dry out.
The dried extract can be smoked pure or in smoking mixes with other herbs like tobacco, cannabis or damiana.
You could also just swallow the extract with some water using the same dosage.